MTL Annual Report

Collaborators

• Jean-Paul Theiry, A*STAR Institute for Molecular and Celllar Biology
• Michael Raghunath, National University of Singapore
• Jeffrey Macklis, Massachusetts General Hospital
• Richard Lee, Brigham and Women’s Hospital
• Harry Asada, MIT, ME
• Douglas Lauffenburger, MIT, BE
• Linda Griffith, MIT, BE

Graduate Students

• Jessie Jeon, Research Assist., ME
• Ioannis Zervantonakis, Research Assist., ME
• Vernella Vickerman, Research Assist., ChemE
• Bill Polacheck, Research Assist., ME

Support Staff

• Annmarie Donovan, Administrative Assistant II

Publications

Vera RH, Genové E, Alvarez L, Borrós S, Kamm R, Lauffenburger D, Semino CE. Interstitial Fluid Flow Intensity Modulates Endothelial Sprouting in Restricted Src-Activated Cell Clusters During Capillary Morphogenesis. Tissue Eng Part A. 2008 Jul 17.

Chung S, Lee JH, Moon M-W, Han J, Kamm RD. Non-lithographic wrinkle nanochannels for protein preconcentration. Adv Mater. 2008, 20:3011-3016.

Das SK, Chung S, Zervantonakis I, Atnafu J, Kamm RD. A microfluidic platform for studying the effects of small temperature gradients in incubator environment. Biomicrofluidics, 2008, 2, 03106.

Chung S, Sudo S, Mack PJ, Wan C-R, Vickerman V, Kamm RD. Cell migration into scaffold under co-culture conditions in a microfluidic platform. Lab Chip, 2009, 9(2):269-75.

Mack PJ, Zhang Y, Chung S, Vickerman V, Kamm RD, Garcia-Cardena G. Biomechanical regulation of endothelium-dependent events critical for adaptive remodeling. J Biol Chem. 2009, 284(13):8412-8420.

Sudo R, Chung S, Zervantonakis IK, Vickerman V, Toshimitsu Y, Griffith LG, Kamm RD. Transport-mediated angiogenesis in 3D epithelial coculture. FASEB J, 2009, 23(7):2155-64.

Chung S, Yun H and Kamm RD. Nanointerstice-driven microflow. Small, 2009, 5(5) 609-13.DOI: 10.1002/smll.200800748.

Chung S, Sudo R, Zervantonakis I, Rimchala T, Kamm RD. Surface-treatment-induced three-dimensional capillary morphogenesis in a microfluidic platform. (Cover Article) Adv Mat, 21: 1-5, 2009. DOI: 10.1002/adma.2009001727

Wood LB, Das A, Kamm RD, Asada HH. A stochastic broadcast feedback approach to regulating cell population morphology for microfluidic angiogenesis platforms. IEEE Trans Biomed Eng. 2009 Sep;56(9):2299-303. Epub 2009 Jul 17.

Mofrad MR, Kamm RD, eds.  Cellular Mechanotransduction: Diverse Perspectives from Molecules to Tissues, Cambridge University Press, 2009.

Chung S, Sudo S, Vickerman V, Zervantonakis IK, Kamm RD.Microfluidic Platforms for Studies of Angiogenesis, Cell Migration, and Cell–Cell Interactions, Annals Biomed Engineering, 2010, DOI: 10.1007/s10439-010-9899-3

Zervantonakis IK, Chung S, Sudo R, Zhang M, Charest JL, Kamm RD. Concentration gradients in microfluidic 3D matrix cell culture systems. Intern J Micro-Nano Scale Transport, 1(1): 27-36, 2010.

Lee H, Ferrer JM, Nakamura F, Lang MJ, Kamm RD. Passive and active microrheology for cross-linked F-actin networks in vitro.  Acta Biomater. 2010 Apr;6(4):1207-1218. Epub 2009 Oct 31