{"id":270,"date":"2010-06-08T15:29:27","date_gmt":"2010-06-08T19:29:27","guid":{"rendered":"https:\/\/wpmu2.mit.local\/?p=270"},"modified":"2010-07-27T11:01:19","modified_gmt":"2010-07-27T15:01:19","slug":"sangeeta-n-bhatia","status":"publish","type":"post","link":"https:\/\/wpmu2.mit.local\/sangeeta-n-bhatia\/","title":{"rendered":"Sangeeta N. Bhatia"},"content":{"rendered":"<div class=\"page-restrict-output\"><h3>Collaborators<\/h3>\n<ul>\n<li>C. Chen, UPenn<\/li>\n<li>B. Engelward, MIT Biological Eng.<\/li>\n<li>T. Golub, Broad Institute<\/li>\n<li>C. Marcus, Harvard<\/li>\n<li>L. Mahadevan, Harvard University<\/li>\n<li>D. Melton, Harvard University<\/li>\n<li>E. Ruoslahti, Burnham Institute<\/li>\n<li>M. Sailor, UCSD<\/li>\n<li>R. Sasisekharan, MIT<\/li>\n<li>P. Sharp, MIT<\/li>\n<li>J. Shah, Harvard<\/li>\n<li>S. Suresh, MIT<\/li>\n<li>K. Van Vliet, MIT<\/li>\n<li>R. Weissleder, HMS<\/li>\n<\/ul>\n<h3>POSTDOCTORAL associates<\/h3>\n<ul>\n<li>N. Singh<\/li>\n<li>D. Wood<\/li>\n<li>S. March<\/li>\n<li>K. Stevens<\/li>\n<li>R. Schwartz<\/li>\n<li>G. Kwong<\/li>\n<\/ul>\n<h3>Graduate Students<\/h3>\n<ul>\n<li>A. Chen, Res. Asst., HST<\/li>\n<li>J. Shan, Res. Asst., HST<\/li>\n<li>Y. Ren, MD\/PhD, HST<\/li>\n<li>N. Reticker-Flynn, Res. Asst., HST<\/li>\n<li>K. Trehan, Res. Asst., HST<\/li>\n<li>K. Lin, Res. Asst., ChemE<\/li>\n<li>C. Li, Res. Asst., ChemE<\/li>\n<li>S. Ng, Res. Asst., BioE<\/li>\n<\/ul>\n<h3>Support Staff<\/h3>\n<ul>\n<li>S. Kangiser, Admin. Asst. II<\/li>\n<li>S. Katz, Laboratory Manager<\/li>\n<li>E. Lehtola, Technical Assistant<\/li>\n<li>G. Underhill, Senior Research Scientist<\/li>\n<\/ul>\n<h3>Publications<\/h3>\n<p>Albrecht, DR, Underhill, GH, Resnikoff, J, Mendelson, A, Bhatia, SN, and Shah, JV (2010 in press): Microfluidics-integrated time-lapse imaging for analysis of cellular dynamics. Integrative Biology.<\/p>\n<p>Jones, CT, Catanese, MT, Law, LMJ, Khetani, SR, Syder, AJ, Ploss, A, Oh, TS, Schoggins, JW, MacDonald, MR, Bhatia, SN, and Rice, CM (2010): Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system. Nature Biotechnology. 28, 167-171<\/p>\n<p>Ploss, A, Khetani, SR, Jones, CT, Sydera, AJ, Trehan, K, Gaysinskaya, VA, Mua, K, Ritola, K, Rice, CM, and Bhatia, SN (2010): Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures. PNAS, published online before print February 1<\/p>\n<p>Harris, TJ, Green, JJ, Fung, PW, Langer, R, Anderson, DG, and Bhatia, SN (2010): Tissue-specific gene delivery via nanoparticle coating. Biomaterials, 31: 998-1006<\/p>\n<p>Park,J-H, von Maltzahn, G, Xu, MJ, Fogal, V, Kotamraju,VR, Ruoslahti, E, Bhatia, SN, &amp; Sailor, MJ (2010): Cooperative nanomaterial system to sensitize, target, and treat tumors. PNAS, 107: 981-986<\/p>\n<p>Agrawal, A, Min, D-H, Singh, N, Zhu, H, Birjiniuk, A,von Maltzahn, G, Harris, T, Xing, D, Woolfenden, S, Sharp, P, Charest, A, and Bhatia, SN (2009): Functional delivery of siRNA in mice using dendriworms. ACS Nano. 3: 2495\u20132504.<\/p>\n<p>March, S, Hui, EE, Underhill, GH, Khetani, S, and Bhatia, SN (2009). Microenvironmental regulation of the sinusoidal endothelial cell phenotype in vitro. Hepatology, 50: 920-928.<\/p>\n<p>von Maltzahn, G, Centrone, A.,Park,J-H, Ramanathan, R, Sailor, MJ, Hatton, TA, and Bhatia, SN (2009): SERS-Coded gold nanorods as a multifunctional platform for densely multiplexed near-infrared imaging and photothermal heating. Advanced Materials, 21: 3175-3180<\/p>\n<p>von Maltzahn, G., Park, J-H, Agrawal, A, Bandaru, NK, Das, SK, Sailor, MJ, and Bhatia, SN (2009 in press):\u00a0 Computationally-guided photothermal tumor therapy using long-circulating gold nanorod antennas. Cancer Research<\/p>\n<p>Higgins , J, Eddington, D , Bhatia, SN, Mahadevan, L (2009): Statistical dynamics of flowing red blood cells by morphological image processing. PLoS Computational Biology. 5 (2), e1000288.<\/p>\n<p>Chen, AA[\u2020], Khetani, SR[\u2020], Lee, S, Bhatia, SN, Van Vliet, KJ (2009, in press): Modulation of hepatocyte phenotype in vitro via chemomechanical tuning of polyelectrolyte multilayers. Biomaterials 30: 1113-1120. [\u2020] These authors contributed equally<\/p>\n<p>J.H. Park, G. von Maltzahn, M.P. Schwartz, E. Ruoslahti, S.N. Bhatia, M.J. Sailor, \u201cMagnetic iron oxide nanoworms for tumor targeting and imaging,\u201d Advanced Materials, vol. 20, no. 9, pp. 1630-1635, May 2008.<\/p>\n<p>Flaim CJ, Teng D, Chien S, and Bhatia, SN (2008). Combinatorial signaling microenvironments for studying stem cell fate. Stem Cells and Development, 17: 1\u201311.<\/p>\n<p>S.R. Khetani and S.N. Bhatia, \u201cMicroscale human liver tissue for drug development,\u201d Nature Biotechnology, vol. 26, no. 1, pp. 120-126, Jan. 2008.<\/p>\n<p>Albrecht, DR, Underhill, GH, Mendelson, A, Bhatia, SN (2007). Multiphase electropatterning of cells and biomaterials. Lab on a Chip, 7: 702 \u2013 709.<\/p>\n<p>A.M. Derfus, A.A. Chen, D.H. Min, E. Ruoslahti, and S.N. Bhatia, \u201cTargeted quantum dot conjugates for siRNA delivery,\u201d Bioconjugate Chemistry, vol. 18, no. 5, pp. 1391-1396, Sept. 2007.<\/p>\n<p>J.M. Higgins, D.T. Eddington, S.N. Bhatia, and L. Mahadevan, \u201cSickle-cell vasoocclusion and rescue in a microfluidic device,\u201d Proc. National Academy of Sciences, vol. 104, no. 51, pp. 20496-20500, Dec. 2007.<\/p>\n<p>A.M. Derfus, G. von Maltzahn, T.J. Harris, T. Duza, K.S. Vecchio, E. Ruoslahti, and S.N. Bhatia, \u201cRemotely triggered release from magnetic nanoparticles,\u201d Advanced Materials, vol. 19, pp. 3932-3936, 2007.<\/p>\n<p>G. von Maltzahn, T.J. Harris, J.H. Park, A.J. Schmidt, M.J. Sailor, and S.N. Bhatia, \u201cNanoparticle self-assembly gated by logical proteolytic triggers,\u201d Journal of the American Chemical Society, vol. 129, pp. 6064-6065, 2007.<\/p>\n<p>E.E. Hui and S.N. Bhatia, \u201cMicromechanical control of cell-cell interactions,\u201d Proc. National Academy of Sciences, vol. 104, pp. 5722-5726, 2007.<\/p>\n<p>V. Liu Tsang, A.A. Chen, L.M. Cho, K.D. Jadin, R.L. Sah, S. DeLong, J.L. West, and S.N. Bhatia, \u201cFabrication of 3D hepatic tissues by additive photopatterning of cellular hydrogels,\u201d FASEB Journal, vol. 21, pp. 790-801, 2007.<\/p>\n<p>S.R. Khetani and S.N. Bhatia, \u201cEngineering tissues for in vitro applications,\u201d Current Opinion in Biotechnology, vol. 17, pp. 524-531, 2006.<\/p>\n<p>D.R. Albrecht, G.H. Underhill, T.B. Wassermann, R.L. Sah, and S.N. Bhatia, \u201cProbing the role of multicellular organization in 3D microenvironments,\u201d Nature Methods, vol. 3, pp. 369-375, Apr. 2006.<\/p>\n<p>T.J. Harris, G. von Maltazhn, A.M. Derfus, E. Rouslahti, and S.N. Bhatia, \u201cProteolytic actuation of nanoparticle self-assembly,\u201d Agnewandte Chemie International Edition, vol. 41, no. 19, pp. 3161-3165, 2006.<\/p>\n<p>J.H. Park, A.M. Derfus, E. Segal, K.S. Vecchio, S.N. Bhatia, and M.J. Sailor, \u201cLocal heating of discrete droplets using magnetic porous silicon-based photonic crystals,\u201d Journal of the American Chemical Society, vol. 128, no. 24, pp. 7938-7946, 2006.<\/p>\n<p>C. Flaim, S. Chien, and S.N. Bhatia, \u201cAn extracellular matrix microarray for probing cellular differentiation,\u201d Nature Methods, vol. 2, no. 2, pp. 119-125, 2005.<\/p>\n<p>J.W. Allen, S.R. Khetani and S.N. Bhatia, \u201cIn vitro zonation and toxicity in a hepatocyte bioreactor,\u201d Toxicological Sciences, vol. 84, pp. 110-119, Mar. 2005.<\/p>\n<p>V. Chin, S. Sanga, P. Taupin, J. Scheel, F.G. Gage, and S.N. Bhatia, \u201cA microfabricated platform for studying stem cell fates,\u201d Biotechnology and Bioengineering, vol. 88, no. 3, pp. 399-415, Mar. 2004.<\/p>\n<p>D. Albrecht, R. Sah and S.N. Bhatia, \u201cGeometric and material determinants of patterning efficiency by dielectrophoresis,\u201d Biophysical Journal, vol. 87, no. 4, pp. 2131-2147, Apr. 2004.<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<div class=\"page-restrict-output\"><p>Micro- and nano-technologies for tissue repair and regeneration. Applications in liver tissue engineering, cell-based BioMEMS, and nanobiotechnology.<\/p>\n<\/div>","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[80],"tags":[43,42],"_links":{"self":[{"href":"https:\/\/wpmu2.mit.local\/wp-json\/wp\/v2\/posts\/270"}],"collection":[{"href":"https:\/\/wpmu2.mit.local\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wpmu2.mit.local\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wpmu2.mit.local\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wpmu2.mit.local\/wp-json\/wp\/v2\/comments?post=270"}],"version-history":[{"count":2,"href":"https:\/\/wpmu2.mit.local\/wp-json\/wp\/v2\/posts\/270\/revisions"}],"predecessor-version":[{"id":2308,"href":"https:\/\/wpmu2.mit.local\/wp-json\/wp\/v2\/posts\/270\/revisions\/2308"}],"wp:attachment":[{"href":"https:\/\/wpmu2.mit.local\/wp-json\/wp\/v2\/media?parent=270"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wpmu2.mit.local\/wp-json\/wp\/v2\/categories?post=270"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wpmu2.mit.local\/wp-json\/wp\/v2\/tags?post=270"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}